How Effective Is Clomid

Clomid is a fertility enhancing drug for women, helpful in condition where women can’t achieve pregnancy normally. This medication is used for solution of ovulation related problems. Results have proved that it is an effective medication for this medical condition. But one can’t accept that whatever said in above lines about clomid till proved. To understand this aspect we take you through work path of this medication.

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Structurally similar to estrogen, this medication works as a selective estrogen modulator, by attaching itself to the estrogen receptor sites in the brain disallowing them to bind with naturally circulating estrogen. In response to effects of this drug, the hypothalamus releases more Gonadotropin Releasing hormone (GnRH), stimulating the pituitary to drain more LH and FSH, which then cause the ovary into producing more eggs and follicles, resulting in ovulation. Generally, a woman taking Clomid doubles or triples the amount of estrogen production in that cycle compared to pretreatment cycles.

In women with irregular menstruation, Clomid helps small and immature follicles grow to maturity (about 20 millimeters in diameter). Also, low estradiol level in a woman's blood correlates with an inadequately stimulated, small follicle. Although she may have enough hormones to produce an egg, but if her estradiol production is low (less than 100 pg/ml), she may not get ready to accept a fertilized egg for implantation. In such candidates, Clomid augments the stimulatory signals from the hypothalamus to the pituitary to the ovaries.

This fertility medication is also often effective in women with luteal phase defect (LPD). LPD causes a break in the natural ovulation process in women resulting in low production of the hormone progesterone in the luteal phase of the menstrual cycle. Clomid has provably enhanced the hypothalamus and pituitary functions so as to keep producing the hormones the ovary needs to manufacture progesterone throughout the luteal phase, resulting in ovulation.

Clomid is very effective in solving ovulation and pregnancy related problems, all this is visible in the positive response it generated in the last decade. The list of satisfied users across the globe of this medication itself speaks its effectiveness.